BFC Firefighters and mutual units were alerted to a motorcycle accident on I-476NB near the Route 1 Interchange during the evening hours.  Arriving units found two subjects ejected from the MC and seriously injured as a result of the crash with another vehicle.  BFC personnel assisted EMS with treatment/packaging of the patients so they could be transported to an area trauma center.  Rescue 53 remained on scene until 0100hrs while PSP investigated the accident.